Sex-peptides bind to two molecularly different targets in Drosophila melanogaster females.

@article{Ding2003SexpeptidesBT,
  title={Sex-peptides bind to two molecularly different targets in Drosophila melanogaster females.},
  author={Zhaobing Ding and Irmgard U. Haussmann and Michael Ottiger and E. Kubli},
  journal={Journal of neurobiology},
  year={2003},
  volume={55 3},
  pages={372-84}
}
Sex-Peptide (SP) and the peptide DUP99B elicit two postmating responses in Drosophila melanogaster females: receptivity is reduced and oviposition is increased. Both are synthesized in the male genital tract and transferred into the female during copulation. To elucidate their function, we characterized the binding properties of SP and DUP99B in females. Cryostat sections of adult females were incubated with alkaline phosphatase (AP)-tagged peptides. In virgin females, both peptides have… CONTINUE READING
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