Sex hormones and the immune response in humans.

@article{Bouman2005SexHA,
  title={Sex hormones and the immune response in humans.},
  author={Annechien Bouman and Maas Jan Heineman and Marijke M. Faas},
  journal={Human reproduction update},
  year={2005},
  volume={11 4},
  pages={
          411-23
        }
}
In addition to their effects on sexual differentiation and reproduction, sex hormones appear to influence the immune system. This results in a sexual dimorphism in the immune response in humans: for instance, females produce more vigorous cellular and more vigorous humoral immune reactions, are more resistant to certain infections, and suffer a higher incidence of autoimmune diseases. Disease expression is also affected by the reproductive status of the female. As sex steroids--estrogens… 
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References

SHOWING 1-10 OF 196 REFERENCES
Sex hormones as immunomodulators in health and disease.
  • D. Verthelyi
  • Biology, Medicine
    International immunopharmacology
  • 2001
In vivo effects of sex steroids on lymphocyte responsiveness and immunoglobulin levels in humans.
TLDR
The results demonstrate that the capacity to develop a TH1 phenotype of peripheral blood lymphocytes is stimulated by androgens and is slightly inhibited by estrogens, which may be direct or indirect through the effects on other hormones.
Sex hormones, immune responses, and autoimmune diseases. Mechanisms of sex hormone action.
TLDR
The possibility of using sex hormone modulation of immune responses for the treatment of autoimmune disorders is a promising area for future investigation.
STUDIES OF THE REGULATORY EFFECTS OF THE SEX HORMONES ON ANTIBODY FORMATION AND STEM CELL DIFFERENTIATION
TLDR
Changes in sex hormone levels exerted a marked influence on immune responsiveness and stem cell differentiation, by increasing numbers of functioning cells, by promoting cellular differentiation, as well as by promotes cellular function via hormonal effects.
Immune cell circulating subsets are affected by gonadal function.
The effect of testosterone on the immune response. 1. Mechanism of action on antibody-forming cells.
TLDR
The effects of orchidectomy and testosterone replacement on the immune response using T-dependent and T-independent antigens were found and an hypothesis that testosterone regulates the immune system through the enhancement of suppressive activity is advanced.
Sex-specific alterations in neutrophil apoptosis: the role of estradiol and progesterone.
TLDR
Female sex hormones mediate delayed neutrophil apoptosis in both sexes and enhance female intracellular production of ROIs andModulating hormonal responses may be an effective therapeutic tool in combating inflammatory diseases.
Estrogen, progesterone, and vascular reactivity: potential cellular mechanisms.
TLDR
The purpose of this review is to provide a framework for identifying the mechanisms by which female sex steroids influence vascular function.
A review of immune cells and molecules in women with recurrent miscarriage.
TLDR
Although much of the evidence is contradictory, these studies do suggest differences in the expression of some immune cells and molecules in women with RM, and the importance of compartment, timing and the timing of the sampling is emphasized.
...
1
2
3
4
5
...