Sex hormones and epididymal sperm parameters in rats following sub-chronic treatment with hexavalent chromium.

@article{Ernst1992SexHA,
  title={Sex hormones and epididymal sperm parameters in rats following sub-chronic treatment with hexavalent chromium.},
  author={Erik Ernst and Jens Peter Ellekilde Bonde},
  journal={Human & experimental toxicology},
  year={1992},
  volume={11 4},
  pages={255-8}
}
Testicular atrophy and reduced epididymal sperm count are known to occur after i.p. administration of high doses of hexavalent chromium to rats. The effect of 0.5 mg kg-1 hexavalent chromium injected i.p. 5 d a week for 8 weeks was investigated in male Wistar rats. A significant reduction in epididymal sperm motility was found at the end of the exposure period. The reduction was reversed after an unexposed period of a further 8 weeks. In addition, a decrease in serum testosterone and an… CONTINUE READING