Sex hormone receptors in breast cancer.

@article{DAbreo2013SexHR,
  title={Sex hormone receptors in breast cancer.},
  author={Nina D'Abreo and Alexander A. Hindenburg},
  journal={Vitamins and hormones},
  year={2013},
  volume={93},
  pages={99-133}
}
The dependency of certain breast cancers on estrogen is undeniably one of the most important observations in oncology. Since this early observation, there has been a tremendous effort to define the precise roles of the estrogen receptor (ER) in the pathogenesis of breast cancer. Estrogen signaling pathways can also be exploited as effective targets for cancer treatment. Both ligand-dependent and ligand-independent receptor activation pathways have been successfully blocked by hormonal therapies… CONTINUE READING

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