Sex hormone modulation of serotonin-induced coronary vasodilation in isolated heart.

@article{Moyss2001SexHM,
  title={Sex hormone modulation of serotonin-induced coronary vasodilation in isolated heart.},
  author={Margareth Ribeiro Moys{\'e}s and Louis A Barker and Antonio De Melo Cabral},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={2001},
  volume={34 7},
  pages={949-58}
}
The present study was designed to evaluate the differences in the coronary vasodilator actions of serotonin (5-HT) in isolated heart obtained from naive or castrated male and female rats that were treated with either estrogen or testosterone. Hearts from 12 groups of rats were used: male and female naive animals, castrated, castrated and treated with 17beta-estradiol (0.5 microg kg(-1) day(-1)) for 7 or 30 days, and castrated and treated with testosterone (0.5 mg kg(-1) day(-1)) for 7 or 30… CONTINUE READING

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