Sex hormone-binding globulin and risk of type 2 diabetes in women and men.

@article{Ding2009SexHG,
  title={Sex hormone-binding globulin and risk of type 2 diabetes in women and men.},
  author={Eric L. Ding and Yiqing Song and Joann E. Manson and David J. Hunter and Cathy Lee and Nader Rifai and Julie E. Buring and J. Michael Gaziano and Simin Liu},
  journal={The New England journal of medicine},
  year={2009},
  volume={361 12},
  pages={1152-63}
}
BACKGROUND Circulating sex hormone-binding globulin levels are inversely associated with insulin resistance, but whether these levels can predict the risk of developing type 2 diabetes is uncertain. METHODS We performed a nested case-control study of postmenopausal women in the Women's Health Study who were not using hormone therapy (359 with newly diagnosed type 2 diabetes and 359 controls). Plasma levels of sex hormone-binding globulin were measured; two polymorphisms of the gene encoding… CONTINUE READING
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