Sex differences in uric acid and risk factors for coronary artery disease.

@article{Tuttle2001SexDI,
  title={Sex differences in uric acid and risk factors for coronary artery disease.},
  author={K. Tuttle and R. Short and R. Johnson},
  journal={The American journal of cardiology},
  year={2001},
  volume={87 12},
  pages={
          1411-4
        }
}
966. 8. Soejima H, Ogawa H, Yasue H, Kaikita K, Takazoe K, Nishiyama K, Misumi K, Miyamoto S, Yoshimura M, Kugiyama K, Nakamura S, Tsuji I. Angiotensinconverting enzyme inhibition reduces monocyte chemoattractant protein-1 and tissue factor levels in patients with myocardial infarction. J Am Coll Cardiol 1999;34:983–988. 9. Brown NJ, Agirbasli M, Vaughan DE. Comparative effect of angiotensinconverting enzyme inhibition and angiotensin II type 1 receptor antagonism on plasma fibrinolytic balance… Expand
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The relation of baseline serum uric acid level to incident coronary heart disease events is described and a growing body of laboratory and clinical evidence suggests that uric Acid plays a role in platelet adhesiveness, formation of free radicals, and oxidative stress. Expand
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Among women, the serum uric acid level was predictive of mortality from all causes and from ischemic heart disease, and these associations persisted even after excluding the first 10 years of follow-up and were independent of use of antihypertensive agents and diuretics, diastolic blood pressure, overweight, and other characteristics. Expand
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Despite blood pressure control, SUA levels increased during treatment and were significantly and directly associated with CVD events, independently of diuretic use and other cardiovascular risk factors. Expand
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The higher serum uric acid concentration seemed associated with elevated total serum antioxidant capacity among individuals with Atherosclerosis, consistent with experimental evidence suggesting that hyperuricemia may be a compensatory mechanism to counteract oxidative damage related to atherosclerosis and aging in humans. Expand
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Urinary albumin excretion and the fasting serum insulin levels were directly related to angiographic evidence of CAD, and microalbuminuria and hyperinsulinemia predict a significantly elevated risk for coronary atherosclerosis. Expand
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The findings suggest that the role of the coronary risk factors on the pathogenesis of coronary atherosclerosis is not uniform but variable depending on the morphologic variability of the Coronary arteriographic features and on the Pathophysiology of the ischemic heart disease. Expand
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Increased serum uric acid levels had a positive relationship to cardiovascular mortality in men and women and in black and white persons and stratifying by cardiovascular risk status, diuretic use, and menopausal status confirmed this relationship. Expand
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