Sex differences in the genetic risk for schizophrenia: history of the evidence for sex-specific and sex-dependent effects.

@article{Goldstein2013SexDI,
  title={Sex differences in the genetic risk for schizophrenia: history of the evidence for sex-specific and sex-dependent effects.},
  author={Jill M. Goldstein and Sara Cherkerzian and Ming T. Tsuang and Tracey L. Petryshen},
  journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics},
  year={2013},
  volume={162B 7},
  pages={698-710}
}
Although there is a long history to examinations of sex differences in the familial (and specifically, genetic) transmission of schizophrenia, there have been few investigators who have systematically and rigorously studied this issue. This is true even in light of population and clinical studies identifying significant sex differences in incidence, expression, neuroanatomic and functional brain abnormalities, and course of schizophrenia. This review highlights the history of work in this arena… CONTINUE READING
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