Sex differences in the development of angiotensin II-induced hypertension in conscious mice.

@article{Xue2005SexDI,
  title={Sex differences in the development of angiotensin II-induced hypertension in conscious mice.},
  author={Baojian Xue and Jaya Pamidimukkala and Meredith Hay},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2005},
  volume={288 5},
  pages={H2177-84}
}
Sex has an important influence on blood pressure (BP) regulation. There is increasing evidence that sex hormones interfere with the renin-angiotensin system. Thus the purpose of this study was to determine whether there are sex differences in the development of ANG II-induced hypertension in conscious male and female mice. We used telemetry implants to measure aortic BP and heart rate (HR) in conscious, freely moving animals. ANG II (800 ng.kg(-1).min(-1)) was delivered via an osmotic pump… CONTINUE READING

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