Sex differences in the contribution of ATP-sensitive K+ channels in trigeminal ganglia under an acute muscle pain condition.

@article{Niu2011SexDI,
  title={Sex differences in the contribution of ATP-sensitive K+ channels in trigeminal ganglia under an acute muscle pain condition.},
  author={Katelyn Y Niu and Jami L Saloman and Yi-Heng Percival Zhang and Jin Young Ro},
  journal={Neuroscience},
  year={2011},
  volume={180},
  pages={344-52}
}
In this study, we examined whether functional subunits of the ATP-dependent K+ channel (KATP) are expressed in trigeminal ganglia (TG), which contains sensory neurons that innervate oral and facial structures. We also investigated whether direct activation of the KATP effectively attenuates mechanical hypersensitivity in the context of an acute orofacial muscle pain condition. The KATP expression in TG and behavioral studies were conducted in age matched male and female Sprague-Dawley rats. RT… CONTINUE READING