Sex differences in gut fermentation and immune parameters in rats fed an oligofructose-supplemented diet

@inproceedings{Shastri2015SexDI,
  title={Sex differences in gut fermentation and immune parameters in rats fed an oligofructose-supplemented diet},
  author={Padmaja Shastri and Justin L. Mccarville and Martin L. Kalmokoff and Stephen P. J. Brooks and Julia M Green-Johnson},
  booktitle={Biology of Sex Differences},
  year={2015}
}
Mechanistic data to support health claims is often generated using rodent models, and the influence of prebiotic supplementation has largely been evaluated using male rodents. Given that sex-based differences in immune parameters are well recognized and recent evidence suggests differences in microbiota composition between sexes, validation of the effectiveness of prebiotics merits assessment in both males and females. Here, we have compared the effect of oligofructose (OF) supplementation on… CONTINUE READING

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