Sex differences in ferric nitrilotriacetate-induced lipid peroxidation and nephrotoxicity in mice.

@article{Li1988SexDI,
  title={Sex differences in ferric nitrilotriacetate-induced lipid peroxidation and nephrotoxicity in mice.},
  author={Jin-Lian Li and Shigeru Okada and Shuji Hamazaki and I L Deng and Osamu Midorikawa},
  journal={Biochimica et biophysica acta},
  year={1988},
  volume={963 1},
  pages={82-7}
}
Since male A/J mice are much more susceptible to both acute and subacute nephrotoxicity and the carcinogenic effect of ferric nitrilotriacetate than female mice, sex differences in the lipid peroxidation level after ferric nitrilotriacetate use were examined. The effects of orchiectomy and testosterone were also investigated. Male and female A/J mice were given a single intraperitoneal injection of ferric nitrilotriacetate (3 mg of iron/kg of body weight) and then thiobarbituric acid reactivity… CONTINUE READING