Sex differences in corpus callosum: Influence of prenatal alcohol exposure and maternal undernutrition

@article{Zimmerberg1990SexDI,
  title={Sex differences in corpus callosum: Influence of prenatal alcohol exposure and maternal undernutrition},
  author={B. Zimmerberg and Lee A. Mickus},
  journal={Brain Research},
  year={1990},
  volume={537},
  pages={115-122}
}
The functional significance of sex differences in the size of the corpus callosum was investigated using a prenatal alcohol exposure paradigm that influences the fetal hormonal milieu. Adult male and female Long-Evans rats were selected from one of 3 prenatal treatment histories: prenatal alcohol-exposed (35% ethanol-derived calories), nutritional control (0% ethanol-derived calories) or standard control (lab chow). Subjects were assessed for open field activity at 85 days of age. At 100 days… Expand
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Results indicate that sex differences in the size of the corpus callosum are present at birth, and the effects of prenatal alcohol exposure on male, but not female, offspring suggest that this alcohol‐related birth defect is hormonally mediated. Expand
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