Sex differences in clinical presentation and response in panic disorder: pooled data from sertraline treatment studies

@article{Clayton2005SexDI,
  title={Sex differences in clinical presentation and response in panic disorder: pooled data from sertraline treatment studies},
  author={Anita H. Clayton and Robert Scott Stewart and Rana S. Fayyad and Cathryn M. Clary},
  journal={Archives of Women's Mental Health},
  year={2005},
  volume={9},
  pages={151-157}
}
SummaryObjective. Gender differences in clinical presentation and response to sertraline treatment were examined for patients diagnosed with DSM-III-R panic disorder with or without agoraphobia. Method. Data was pooled from 4 double-blind, placebo-controlled outpatient studies (males, N = 335; females, N = 338). Two were 12-week fixed-dose studies (sertraline 50 mg vs. 100 mg vs. 200 mg) and 2 were 10-week flexible-dose studies (sertraline 50–200 mg). Primary outcome measures consisted of the… 
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Highly Influential Citations
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Results Citations
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36 Citations

[Gender differences in psychopathologic features of agoraphobia with panic disorder].
TLDR
The women, howerer, reported a subjective perception of a more severe agoraphobic avoidance and males were significantly more likely than the females to anticipate the serious somatic consequences of panic attacks and worry about somatic health.
Panic disorder, agoraphobia, comorbidity
TLDR
Nearly half of the PD patients had major depression, while in patients with comorbid agoraphobia, prevalence ofComorbid disorders, particularly of SAD, was shown to increase and rates for generalized anxiety disorder and social anxiety disorder were found to be lower than groups in similar literature.
Co-occurrence of Axis I and Axis II disorders in female and male patients with panic disorder with agoraphobia.
Characteristics and Comorbidity in Panic Disorder Patients
TLDR
Nearly half of the PD patients had major depression, while in patients with comorbid Axis I psychiatric disorder, the rate of major depression was compatible with the literature, while comorebidity rates for generalized anxiety disorder and social anxiety disorder were found to be lower than the groups in similar literature.
Personalized medicine in panic disorder: where are we now? A meta-regression analysis
HSOA Journal of Psychiatry, Depression & Anxiety Sex Differences in Anxiety Disorders: A Review
Women have consistently shown to be more likely than men to meet criteria for the diagnosis of an anxiety disorder during their lifetime. Prior research has demonstrated that presence of an anxiety…
Title Gender-specific abnormalities in the serotonin transportersystem in panic disorder
TLDR
The finding that 5-HTT-binding is elevated in males but not in females with PD converges with other evidence suggesting that dysfunction within the central serotonergic system exists in PD, and indicates that such abnormalities are influenced by gender.
Sociodemographic characteristics and comorbidity in panic disorder patients / Panik bozukluğu hastalarında sosyodemografik özellikler ve komorbidite
TLDR
Nearly half of the PD patients had major depression, while in patients with comorbid agoraphobia, prevalence ofComorbid disorders, particularly of SAD, was shown to increase and rates for generalized anxiety disorder and social anxiety disorder were found to be lower than groups in similar literature.
Panic attacks and panic disorder in the American Indian community.
Gender-specific abnormalities in the serotonin transporter system in panic disorder.
TLDR
The finding that 5-HTT-binding is elevated in males but not in females with PD converges with other evidence suggesting that dysfunction within the central serotonergic system exists in PD, and indicates that such abnormalities are influenced by gender.
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