Sex differences in cell death.

  title={Sex differences in cell death.},
  author={Hong Li and Scott Pin and Zhiyuan Zeng and Michael Mei-Hwa Wang and Katrin A Andreasson and Louise D McCullough},
  journal={Annals of neurology},
  volume={58 2},
Female patients experience substantial neuroprotection after experimental stroke compared with male patients, a finding attributed to the protective effects of gonadal hormones. This study examined the response of male- and female-derived organotypic hippocampal slices to oxidative and excitotoxic injury. Both oxygen and glucose deprivation and N-methyl-D-aspartic acid exposure led to neuronal death; however, female-derived cultures sustained less injury than male-derived cultures. Cell death… CONTINUE READING


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