Sex differences in behavioral, neurochemical and neuroendocrine effects induced by the forced swim test in rats.

@article{Drossopoulou2004SexDI,
  title={Sex differences in behavioral, neurochemical and neuroendocrine effects induced by the forced swim test in rats.},
  author={Garyfallia I Drossopoulou and Katerina Antoniou and Efthimia Kitraki and Georgia Papathanasiou and Eugenia Papalexi and Christina Dalla and Zeta Papadopoulou-Daifoti},
  journal={Neuroscience},
  year={2004},
  volume={126 4},
  pages={849-57}
}
The forced swim test (FST) has been considered as a pharmacologically valid test of the depressive syndrome in rodents. However, few studies have focused on neurochemical and behavioral responses during FST in both male and female rats. Thus, we investigated certain behavioral and neuroendocrine responses as well as the serotonergic activity after the application of FST in both sexes. Our data show that the duration of immobility was increased in both male and female rats during the 2nd session… CONTINUE READING