Sex differences in autoimmune disease
@article{Whitacre2001SexDI, title={Sex differences in autoimmune disease}, author={Caroline C. Whitacre}, journal={Nature Immunology}, year={2001}, volume={2}, pages={777-780} }
Autoimmune diseases are more prevalent in women than men. A new interest in understanding the biology of this difference as well as funding opportunities have focused attention on research priorities in sex differences.
1,179 Citations
Women and Autoimmune Diseases
- Biology, MedicineEmerging infectious diseases
- 2004
Recent evidence indicates that sex hormones may exacerbate autoimmune diseases, particularly in women, by increasing the adjuvant effect of infections.
Sex and Gender Differences in Autoimmune Diseases
- Medicine, Biology
- 2012
This research highlights the need to understand more fully the role that gender plays in the development of immune and rheumatological diseases.
Sex differences in monocyte expression of IL-6: Role of autonomic mechanisms
- Biology, Psychology
- 2007
Sex differences in the prevalence of inflammatory disorders exist, perhaps due to sex differences in cellular mechanisms that contribute to proinflammatory cytokine activity. This study analyzed se...
Factors Which Predispose to the Onset of Autoimmune Disease
- Medicine
- 2005
This project was carried out in Dr. Caroline Whitacre's Lab in the Department of Molecular Virology, Immunology and Medical Genetics (College of Medicine and Public Health, The Ohio State University).
Can we explain the higher prevalence of autoimmune disease in women?
- MedicineExpert review of clinical immunology
- 2010
The notion that ADs affect females more frequently than men has been striking clinicians for many years, and this predominance may vary from 9:1 in systemic lupus erythematosus, Sjogren’s syndrome and primary biliary cirrhosis, down to 1: 1 in inflammatory bowl disease and Type 1 diabetes mellitus.
Contributing factors in multiple sclerosis and the female sex bias.
- Psychology, BiologyImmunology letters
- 2014
Gender and Inflammatory Bowel Disease
- Medicine
- 2014
This review focuses on the gender and sex dimorphic disease profile and outlines the potential mechanisms ofsex-specific pathogenesis in the view of current understanding of sex-specific immunity.
Age of puberty and the risk of multiple sclerosis: a population based study
- Medicine, PsychologyEuropean journal of neurology
- 2009
This work has investigated whether or not the age of puberty influences the risk of developing MS in a population‐based cohort and found that it does not.
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