Sex differences in autoimmune disease

@article{Whitacre2001SexDI,
  title={Sex differences in autoimmune disease},
  author={Caroline C. Whitacre},
  journal={Nature Immunology},
  year={2001},
  volume={2},
  pages={777-780}
}
  • C. Whitacre
  • Published 1 September 2001
  • Biology, Medicine, Psychology
  • Nature Immunology
Autoimmune diseases are more prevalent in women than men. A new interest in understanding the biology of this difference as well as funding opportunities have focused attention on research priorities in sex differences. 
Women and Autoimmune Diseases
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Factors Which Predispose to the Onset of Autoimmune Disease
This project was carried out in Dr. Caroline Whitacre's Lab in the Department of Molecular Virology, Immunology and Medical Genetics (College of Medicine and Public Health, The Ohio State University).
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The notion that ADs affect females more frequently than men has been striking clinicians for many years, and this predominance may vary from 9:1 in systemic lupus erythematosus, Sjogren’s syndrome and primary biliary cirrhosis, down to 1: 1 in inflammatory bowl disease and Type 1 diabetes mellitus.
Testosterone: more than having the guts to win the Tour de France.
Gender and Inflammatory Bowel Disease
TLDR
This review focuses on the gender and sex dimorphic disease profile and outlines the potential mechanisms ofsex-specific pathogenesis in the view of current understanding of sex-specific immunity.
Age of puberty and the risk of multiple sclerosis: a population based study
TLDR
This work has investigated whether or not the age of puberty influences the risk of developing MS in a population‐based cohort and found that it does not.
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In a Perspective in this issue, Caroline Whitacre and her fellow members of the Task Force on Gender, Multiple Sclerosis and Autoimmunity explain what the authors currently know about gender differences in autoimmunities and discuss priorities for future research.
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TLDR
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