Sex differences in anxiety, sensorimotor gating and expression of the alpha4 subunit of the GABAA receptor in the amygdala after progesterone withdrawal.

@article{Gulinello2003SexDI,
  title={Sex differences in anxiety, sensorimotor gating and expression of the alpha4 subunit of the GABAA receptor in the amygdala after progesterone withdrawal.},
  author={Maria Gulinello and Rena Orman and Sheryl Sue Smith},
  journal={The European journal of neuroscience},
  year={2003},
  volume={17 3},
  pages={641-8}
}
In a progesterone withdrawal (PWD) model of premenstrual anxiety, we have previously demonstrated that increased hippocampal expression of the alpha4 subunit of the GABAA receptor (GABAA-R) is closely associated with higher anxiety levels in the elevated plus maze. However, several studies indicate that sex differences in regulation of the GABAA-R in… CONTINUE READING