Sex differences in Parkinson's disease and other movement disorders.

@article{Smith2014SexDI,
  title={Sex differences in Parkinson's disease and other movement disorders.},
  author={Kara M. Smith and Nabila A Dahodwala},
  journal={Experimental neurology},
  year={2014},
  volume={259},
  pages={44-56}
}
Movement disorders including Parkinson's disease (PD), Huntington's disease (HD), chorea, tics, and Tourette's syndrome (TS) display sex differences in disease susceptibility, disease pathogenesis, and clinical presentation. PD is more common in males than in females. Epidemiologic studies suggest that exposure to endogenous and exogenous estrogen contributes to these sex differences. There is extensive evidence that estrogen prevents dopaminergic neuron depletion induced by neurotoxins in PD… CONTINUE READING