Sex differences and estrous cycle variations in amphetamine-elicited rotational behavior.

@article{Becker1982SexDA,
  title={Sex differences and estrous cycle variations in amphetamine-elicited rotational behavior.},
  author={Jill B Becker and Terry E. Robinson and Kerstin Lorenz},
  journal={European journal of pharmacology},
  year={1982},
  volume={80 1},
  pages={65-72}
}
The experiments reported here were designed to determine if there are sex- and/or estrus cycle-dependent differences in amphetamine (AMPH)-elicited rotational behavior in unlesioned rats. Whole brain or striatal levels of AMPH produced by systemic administration of the drug were also measured. At all doses tested (1.0-10.0 mg/kg) systemic administration of AMPH resulted in significantly higher brain levels of AMPH in females than in males. A systemic dose was then calculated which produced… CONTINUE READING

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