Sex differences, context preexposure, and the immediate shock deficit in Pavlovian context conditioning with mice.

@article{Wiltgen2001SexDC,
  title={Sex differences, context preexposure, and the immediate shock deficit in Pavlovian context conditioning with mice.},
  author={Brian J. Wiltgen and Mathew J. Sanders and Nicole Behne and Michael S Fanselow},
  journal={Behavioral neuroscience},
  year={2001},
  volume={115 1},
  pages={26-32}
}
The acquisition of context fear in rats is affected by variables such as the sex of the animal, the placement to shock interval (PSI), and preexposure to the context. The current experiments assessed the effects of these variables on context conditioning in mice (C57BL/6). In Experiment 1, mice were placed in a chamber and received a single shock 5s, 20 s, 40s, 60s, 180s, or 720s later. Increasing the PSI produced corresponding increases in conditional freezing during the context test. In… CONTINUE READING

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