Sex determines the expression level of one third of the actively expressed genes in bovine blastocysts

@article{Bermejolvarez2010SexDT,
  title={Sex determines the expression level of one third of the actively expressed genes in bovine blastocysts},
  author={P. Bermejo-{\'A}lvarez and D. Rizos and D. Rath and P. Lonergan and A. Guti{\'e}rrez-Ad{\'a}n},
  journal={Proceedings of the National Academy of Sciences},
  year={2010},
  volume={107},
  pages={3394 - 3399}
}
Although genetically identical for autosomal Chrs (Chr), male and female preimplantation embryos could display sex-specific transcriptional regulation. To illustrate sex-specific differences at the mRNA level, we compared gene-expression patterns between male and female blastocysts by DNA microarray comparison of nine groups of 60 bovine in vitro-produced blastocysts of each sex. Almost one-third of the transcripts detected showed sexual dimorphism (2,921 transcripts; false-discovery rate, P… Expand
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