Sex-dependent toxoplasmosis-associated differences in testosterone concentration in humans

@article{Flegr2008SexdependentTD,
  title={Sex-dependent toxoplasmosis-associated differences in testosterone concentration in humans},
  author={Jaroslav Flegr and Jitka Lindov{\'a} and Petr Kodym},
  journal={Parasitology},
  year={2008},
  volume={135},
  pages={427 - 431}
}
SUMMARY Several lines of indirect evidence suggest that subjects with latent infection of the coccidian parasite Toxoplasma gondii have a higher concentration of testosterone than uninfected controls. Here, we searched for direct evidence of latent toxoplasmosis-associated differences in testosterone concentration among a population of 174 female and 91 male students screened for Toxoplasma infection. We have found Toxoplasma-infected men to have a higher concentration of testosterone and… Expand
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Testosterone concentration in study group was higher than that in control group with statistically significant difference, and significant differences were found in testosterone concentrations and anti-Toxoplasma IgG antibody levels in study and control groups. Expand
The effects of toxoplasmosis on sex ratio at birth.
TLDR
The effect of prevalence of toxoplasmosis on a nationwide sex ratio was the third strongest effect from the effects of 15 factors included in the analysis, and it has been suggested that toxoplasma-associated concentration of steroid hormones or glucose may be the proximal cause in the sex ratio shift. Expand
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It is shown that Toxoplasma gondii infection enhances expression of genes involved in facilitating synthesis of testosterone, resulting in greater testicular testosterone production in male rats, suggesting that parasites may manipulate trade‐offs in rats. Expand
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TLDR
Latent toxoplasmosis has immunomodulatory effects in human and probably protects men against some classes of immunopathological diseases. Expand
Some Hormonal Assay in Toxoplasma Infected University Students
TLDR
It has been concluded that chronic toxoplasmosis can affect some hormonal concentration in human blood which may change or influence human behavior. Expand
Toxoplasma gondii and Psychopathology: Latent Infection Is Associated with Interpersonal Sensitivity, Psychoticism, and Higher Testosterone Levels in Men, but Not in Women
Objective The ability of parasites to hijack the nervous system, manipulating the host’s physiology and behavior in ways that enhance the parasite’s fitness while damaging host fitness, is a topic ofExpand
Study of latent Toxoplasma gondii role in level of testosterone, DHEA, cortisol and prolactin hormones of young persons
TLDR
The direct correlation between toxoplasmosis and psychological disorders is suggested due to effect of Toxoplasma on host’s hormone levels. Expand
Toxoplasma, testosterone, and behavior manipulation: the role of parasite strain, host variations, and intensity of infection
TLDR
The role of parasite strains, host variations, and intensity of T. gondii infection on behavioral alterations and testosterone production, as well as the role of testosterone in the etiology of these alterations during toxoplasmosis are reviewed. Expand
Effects of Toxoplasma gondii Infection in Level of Serum Testosterone in Males with Chronic Toxoplasmosis
TLDR
The chronic toxoplasmosis could affect reproductive parameters in men with high serum levels of testosterone and this difference was statistically significant (P<0.05). Expand
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