Sex-dependent expression of placental (P)-cadherin during mouse gonadogenesis.

BACKGROUND Placental (P)-cadherin is one of a family of cell adhesion molecules that participate in embryonic sorting and organogenesis. In previous work, P-cadherin was localized to Sertoli cells in the mouse testis as early as postnatal day 1. This early postnatal localization raised questions about when P-cadherin first appeared in the embryonic testis… CONTINUE READING