Sex-dependent effects of gonadal steroids and cortisol on cardiac contractility in rainbow trout.

@article{Farrar2004SexdependentEO,
  title={Sex-dependent effects of gonadal steroids and cortisol on cardiac contractility in rainbow trout.},
  author={Richard S Farrar and Kenneth J. Rodnick},
  journal={The Journal of experimental biology},
  year={2004},
  volume={207 Pt 12},
  pages={2083-93}
}
The purpose of this study was to determine whether steroid hormones modulate cardiac function in rainbow trout (Oncorhynchus mykiss Walbaum). We assessed the effects of exogenously administered steroids on isolated ventricle strips and report that physiological concentrations of androgens, 17beta-estradiol and cortisol rapidly (<10 min) enhance inotropism (30-40%) in a sex-specific manner. These effects were specific to the hormones studied, absent if animals were anesthetized chemically and… CONTINUE READING
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