Sex and strain influence attribution of incentive salience to reward cues in mice

  title={Sex and strain influence attribution of incentive salience to reward cues in mice},
  author={Price E Dickson and Kathryn A McNaughton and Lingfeng Hou and Laura C. Anderson and Katie Long and Elissa J. Chesler},
  journal={Behavioural Brain Research},
The propensity to attribute incentive salience to reward cues, measured by Pavlovian sign-tracking, is strongly associated with addiction-related traits including cocaine self-administration, impulsivity, novelty reactivity, and novelty preference. Despite its critical role in addiction, the genetic underpinnings of incentive salience attribution and its relationship to drug addiction are unknown. Mouse genetics can be a powerful means to discover genetic mechanisms underlying this relationship… CONTINUE READING

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