Sex Specification and Heterogeneity of Primordial Germ Cells in Mice.

@article{Sakashita2015SexSA,
  title={Sex Specification and Heterogeneity of Primordial Germ Cells in Mice.},
  author={Akihiko Sakashita and Yukiko Kawabata and Yuko Jincho and Shiun Tajima and Soichiro Kumamoto and Hisato Kobayashi and Yasuhisa Matsui and Tomohiro Kono},
  journal={PloS one},
  year={2015},
  volume={10 12},
  pages={e0144836}
}
In mice, primordial germ cells migrate into the genital ridges by embryonic day 13.5 (E13.5), where they are then subjected to a sex-specific fate with female and male primordial germ cells undergoing mitotic arrest and meiosis, respectively. However, the sex-specific basis of primordial germ cell differentiation is poorly understood. The aim of this study was to investigate the sex-specific features of mouse primordial germ cells. We performed RNA-sequencing (seq) of E13.5 female and male… CONTINUE READING
Highly Cited
This paper has 57 citations. REVIEW CITATIONS
Related Discussions
This paper has been referenced on Twitter 7 times. VIEW TWEETS

Citations

Publications citing this paper.

58 Citations

050100150201720182019
Citations per Year
Semantic Scholar estimates that this publication has 58 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 55 references

A role for retrotransposon LINE-1 in fetal oocyte attrition in mice

S Malki
Dev Cell, • 2014
View 1 Excerpt

A set of genes critical to development is epigenetically poised in mouse germ cells from fetal stages through completion of meiosis

Lesch B.J
Proc Natl Acad Sci U S A, • 2013
View 1 Excerpt

Similar Papers

Loading similar papers…