Sex-Specific Urinary Biomarkers for Diagnosing Bipolar Disorder

  title={Sex-Specific Urinary Biomarkers for Diagnosing Bipolar Disorder},
  author={Jizheng Chen and Hua Huang and Li-bo Zhao and De-zhi Zhou and Yong-tao Yang and Peng Zheng and De-yu Yang and Peng He and Jing-Jing Zhou and Liang Fang and Peng Xie},
  booktitle={PloS one},
Sex-based differences are prominent in affective disorders, but there are no biomarkers available to support sex-specific, laboratory-based diagnostics for male and female bipolar disorder (BD) patients. Here, a NMR-based metabonomic approach was used to preliminarily identify sex-specific urinary metabolite biomarkers for diagnosing male and female BD patients. A male-specific biomarker panel consisting of four metabolites (α-hydroxybutyrate, choline, formate, and N-methylnicotinamide… CONTINUE READING
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