• DOI:10.1016/j.cell.2006.02.024
Corpus ID: 8379688

Sex Chromosome Specialization and Degeneration in Mammals

@article{Graves2006SexCS,
  title={Sex Chromosome Specialization and Degeneration in Mammals},
  author={J. Graves},
  journal={Cell},
  year={2006},
  volume={124},
  pages={901-914}
}

J. Graves

Published 2006

Biology, Medicine

Cell

Sex chromosomes--particularly the human Y--have been a source of fascination for decades because of their unique transmission patterns and their peculiar cytology. The outpouring of genomic data confirms that their atypical structure and gene composition break the rules of genome organization, function, and evolution. The X has been shaped by dosage differences to have a biased gene content and to be subject to inactivation in females. The Y chromosome seems to be a product of a perverse… CONTINUE READING

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