Sex, stress and the hippocampus: allostasis, allostatic load and the aging process

@article{McEwen2002SexSA,
  title={Sex, stress and the hippocampus: allostasis, allostatic load and the aging process},
  author={B. McEwen},
  journal={Neurobiology of Aging},
  year={2002},
  volume={23},
  pages={921-939}
}
  • B. McEwen
  • Published 2002
  • Psychology, Medicine
  • Neurobiology of Aging
The adaptive responses of the body that maintain homeostasis in response to stressors can be called "allostasis", meaning "achieving stability through change". Mediators produced by the immune system, autonomic nervous system (ANS) and hypothalamo-pituitary-adrenal(HPA) axis produce allostasis. The brain also shows allostasis, involving the activation of nerve cell activity and the release of neurotransmitters. When the individual is challenged repeatedly or when the allostatic systems remain… Expand
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