Sevoflurane pretreatment enhance HIF-2α expression in mice after renal ischemia/reperfusion injury.

@article{Zheng2015SevofluranePE,
  title={Sevoflurane pretreatment enhance HIF-2α expression in mice after renal ischemia/reperfusion injury.},
  author={Beijie Zheng and Qionghui Zhan and J Chen and Huan Xu and Zhenzhou He},
  journal={International journal of clinical and experimental pathology},
  year={2015},
  volume={8 10},
  pages={13114-9}
}
Ischemia/reperfusion (I/R) injury often occurs, which is one of the major causes of acute kidney injury, thus increasing in-hospital mortality. HIF-2α has a protective role against ischemia of the kidney. Renal ischemia/reperfusion under sevoflurane anesthesia resulted in drastic improvements in renal function. We hypothesized that underlying mechanism… CONTINUE READING