Sevoflurane Blocks the Induction of Long-term Potentiation When Present during, but Not When Present Only before, the High-frequency Stimulation

@article{Liu2018SevofluraneBT,
  title={Sevoflurane Blocks the Induction of Long-term Potentiation When Present during, but Not When Present Only before, the High-frequency Stimulation},
  author={Jinyang Liu and Lie Yang and D. Lin and J. Cottrell and I. S. Kass},
  journal={Anesthesiology},
  year={2018},
  volume={128},
  pages={555–563}
}
Background: This study tests the hypothesis that sevoflurane blocks long-term potentiation only if it is present during the high-frequency stimulation that induces long-term potentiation. Methods: Long-term potentiation, an electrophysiologic correlate of memory, was induced by high-frequency stimulation and measured as a persistent increase in the field excitatory postsynaptic potential slope in the CA1 region. Results: Long-term potentiation was induced in the no sevoflurane group (171 ± 58… Expand
2 Citations
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  • P. Loprinzi
  • Medicine
  • Advances in experimental medicine and biology
  • 2020

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