Sevoflurane: A New Inhalational Anesthetic Agent

@article{Wallin1975SevofluraneAN,
  title={Sevoflurane: A New Inhalational Anesthetic Agent},
  author={R. F. Wallin and B. Regan and I. Stern},
  journal={Anesthesia \& Analgesia},
  year={1975},
  volume={54},
  pages={758–766}
}
Laboratory screening of a series of halogenated methyl isopropyl ethers revealed sevoflurane (fluoromethyl-1, 1,1,3,3,3,-hexafluoro-2-propyl ether) as a potent nonexplosive inhalational anesthetic agent. Sevoflurane, a pleasant-smelling liquid, boils at 58.5°C at 760 torr and has a vapor pressure of 200 torr at 25°C. It is nonflammable in air and has lower flammability limits of 11 vols percent in O2 and 10 vols percent in N2O.Sevoflurane exhibits limited chemical reactivity in vitro; it is… Expand
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