Severity of cystic fibrosis in patients homozygous and heterozygous for delta F508 mutation.

@article{Johansen1991SeverityOC,
  title={Severity of cystic fibrosis in patients homozygous and heterozygous for delta F508 mutation.},
  author={Helle Krogh Johansen and Mark A. Nir and Niels H\oiby and Christian Koch and Marianne Schwartz},
  journal={Lancet},
  year={1991},
  volume={337 8742},
  pages={
          631-4
        }
}
To assess the relation between genotype and severity of disease in cystic fibrosis (CF) the frequencies and extent of several features of its phenotypic expression were investigated in the 235 patients who attend the Danish CF Centre. 14 patients who attend irregularly and 3 who do not carry the delta F508 mutation at all were excluded. The case-reports of the remaining 218 patients (aged 4 months to 41 years) were carefully evaluated, and they were all analysed for the delta F508 mutation. 172… CONTINUE READING
Highly Cited
This paper has 43 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations