Severely reduced presence of tissue macrophages in the basal plate of pre-eclamptic placentae.

@article{Brk2001SeverelyRP,
  title={Severely reduced presence of tissue macrophages in the basal plate of pre-eclamptic placentae.},
  author={Martin R. B{\"u}rk and Carolyn Troeger and R Brinkhaus and Wolfgang Holzgreve and Sinuhe Hahn},
  journal={Placenta},
  year={2001},
  volume={22 4},
  pages={
          309-16
        }
}
Pre-eclampsia is a disorder of unknown aetiology peculiar to human pregnancy. A well-described pathological feature being shallow trophoblast invasion into the spiral arteries during placenta development. Epidemiological studies have revealed an increased risk in pregnancies of primipaternity, and an association with the maternal-fetal HLA-DR relationship, both suggesting the involvement of an immunological component. We were therefore interested in the distribution of HLA-DR expressing myeloid… CONTINUE READING
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