Severe ulcerative colitis: a personal point of view.

  title={Severe ulcerative colitis: a personal point of view.},
  author={Cosimo Prantera and Roberto Lorenzetti},
  volume={36 4},
In the course of their disease about 15% of all ulcerative colitis patients have a severe attack with evidence of systemic toxicity. On the basis of our personal experience of a recent series of 46 patients, and of a review of the literature, several conclusions can be drawn. A number of more severe attacks (28 out of 46 patients in our series), defined as "fulminating" or "toxic" colitis, must be regarded as major determinants of complications and mortality (4.3% in our series). The disease… CONTINUE READING