Severe tumor lysis syndrome during treatment with STI 571 in a patient with chronic myelogenous leukemia accelerated phase.

@article{Vora2002SevereTL,
  title={Severe tumor lysis syndrome during treatment with STI 571 in a patient with chronic myelogenous leukemia accelerated phase.},
  author={Amishi Vijay Vora and Manisha Bhutani and A. K. Sharma and Vinod Raina},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2002},
  volume={13 11},
  pages={
          1833-4
        }
}
  • A. Vora, M. Bhutani, V. Raina
  • Published 1 November 2002
  • Medicine
  • Annals of oncology : official journal of the European Society for Medical Oncology
Signal transduction inhibitor 571 (STI 571), a potent and selective inhibitor of the tyrosine kinase activity of BCR– ABL, is an important advance in the treatment of chronic myelogenous leukemia (CML) patients in the advanced phase of disease or those with chronic phase (CP) intolerant or resistant to interferon (IFN) therapy [1–3]. Given at the dose of 400–600 mg p.o. daily, STI 571 is generally well tolerated. Common adverse effects include mild to moderate myelosuppression, nausea, vomiting… 
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DOI: 10.1093/annonc
  • DOI: 10.1093/annonc