Severe transient hypoglycemia causes reversible change in the apparent diffusion coefficient of water.

@article{Hasegawa1996SevereTH,
  title={Severe transient hypoglycemia causes reversible change in the apparent diffusion coefficient of water.},
  author={Yasuhiro Hasegawa and James E. Formato and Lawrence L. Latour and Jorge A. Gutierrez and Katharine Liu and Julio H. Garcia and Christopher H. Sotak and Marc Fisher},
  journal={Stroke},
  year={1996},
  volume={27 9},
  pages={
          1648-55; discussion 1655-6
        }
}
BACKGROUND AND PURPOSE The aim of this study was to determine the effects of temporary severe hypoglycemia on the apparent diffusion coefficient (ADC) acquired by diffusion-weighted MRI of brain water with the use of serial multislice ADC mapping in rats. Severe hypoglycemia reduces the extracellular space volume, as does ischemia. Demonstrating a reduction of ADC with hypoglycemia should increase our understanding of the mechanisms underlying ADC changes in ischemia and other conditions… CONTINUE READING
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