Severe subcortical degeneration in macaques infected with neurovirulent simian immunodeficiency virus

@article{Marcario2004SevereSD,
  title={Severe subcortical degeneration in macaques infected with neurovirulent simian immunodeficiency virus},
  author={Joanne K. Marcario and Kebreten F. Manaye and Karen S Santacruz and Peter R. Mouton and Nancy E. J. Berman and Paul D Cheney},
  journal={Journal of NeuroVirology},
  year={2004},
  volume={10},
  pages={387-399}
}
Infection with human immunodeficiency virus-1 (HIV-1), the causative agent of acquired immunodeficiency syndrome (AIDS) in humans, causes a spectrum of neuropathology that includes alterations in behavior, changes in evoked potentials, and neuronal degeneration. In the simian immunodeficiency virus (SIV) model of HIV infection, affected monkeys show clinical symptoms and neurological complications that mimic those observed in human neuro-AIDS. To investigate the relationship between… CONTINUE READING
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