Severe propylthiouracil-induced hepatotoxicity in pregnancy managed successfully by liver transplantation: A case report

@inproceedings{Sequeira2011SeverePH,
  title={Severe propylthiouracil-induced hepatotoxicity in pregnancy managed successfully by liver transplantation: A case report},
  author={Evan Sequeira and Sikolia Z. Wanyonyi and Raj Hasmukh Dodia},
  booktitle={Journal of medical case reports},
  year={2011}
}
IntroductionPropylthiouracil-induced severe hepatotoxicity is a relatively rare occurrence, with very few cases reported in the literature. The management of this complication in pregnancy can be a challenge because of the effects of the various treatment options on the fetus.Case presentationWe report a rare case of fulminant hepatic failure in a 36-year-old gravida 2 black woman of African descent that occurred at 17 weeks gestation following propylthiouracil treatment for Graves' disease… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 12 CITATIONS

EASL Clinical Practice Guidelines: Drug-induced liver injury.

VIEW 1 EXCERPT
CITES BACKGROUND

Gestational thyrotoxicosis, antithyroid drug use and neonatal outcomes within an integrated healthcare delivery system.

VIEW 1 EXCERPT
CITES BACKGROUND

Propylthiouracil, and methimazole, and carbimazole-related hepatotoxicity.

VIEW 2 EXCERPTS
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 15 REFERENCES

Antithyroid drugs

  • DS Cooper
  • N Engl J Med
  • 2005
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Pregnancy outcomes among liver transplant recipients in the United States: a nationwide case-control analysis.

VIEW 2 EXCERPTS

Successful management of a same-day emergency delivery and liver transplant in a 27 weeks pregnant woman with fulminant hepatic failure.

VIEW 2 EXCERPTS

Association and the Food and Drug Administration

  • DS Cooper
  • 2009

Liver transplantation for acute liver failure from drug induced liver injury in the United States.

VIEW 1 EXCERPT