Severe phototoxicity associated with long-term voriconazole treatment.

  title={Severe phototoxicity associated with long-term voriconazole treatment.},
  author={Sabine V{\"o}hringer and Johanna Schrum and Hagen Ott and Peter Hans Hoeger},
  journal={Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG},
  volume={9 4},
Voriconazole is a second-generation triazole antifungal approved for the treatment of invasive fungal infections, particularly with Aspergillus, Candida, Fusarium, and Scedosporium spp. Frequently reported adverse effects of voriconazole include visual disturbance (21 %), elevated liver enzymes (15.6 %) and rashes (7 %), which are largely attributable to drug-induced photosensitivity. We report a case of serious phototoxicity in a 8 year old boy who underwent chemotherapy for AML. He received… CONTINUE READING


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