Severe obesity is associated with novel single nucleotide polymorphisms of the ESR1 and PPARgamma locus in Han Chinese.

@article{Chen2009SevereOI,
  title={Severe obesity is associated with novel single nucleotide polymorphisms of the ESR1 and PPARgamma locus in Han Chinese.},
  author={Hsin-Hung Chen and Wei-Jei Lee and Cathy Shen-Jang Fann and Claude Bouchard and Wen-Harn Pan},
  journal={The American journal of clinical nutrition},
  year={2009},
  volume={90 2},
  pages={255-62}
}
BACKGROUND A large number of potential obesity loci have been reported. At least 18 genes have been replicated in a minimum of 5 studies on obesity-related phenotypes. Fourteen additional genes have been associated with obesity in Asians. OBJECTIVES Our objectives were to examine how many common variants of these candidate genes are associated with severe obesity in Han Chinese and how they are combined to exert their effects. DESIGN In total, 304 severely obese patients [body mass index… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Similar Papers

Loading similar papers…