Severe midline craniofacial anomalies: overlap with Pai syndrome.

@article{GuionAlmeida2009SevereMC,
  title={Severe midline craniofacial anomalies: overlap with Pai syndrome.},
  author={Maria Leine Guion-Almeida and Ant{\^o}nio Richieri-Costa},
  journal={Clinical dysmorphology},
  year={2009},
  volume={18 3},
  pages={154-7}
}
Introduction Midline cleft lip with premaxillary involvement can be part of the clinical spectrum of several syndromes among the syndromes of the frontonasal dysplasia (FND) spectrum (Gorlin et al., 2001). FND is usually reported as an isolated field defect, resulting from the abnormal morphogenesis of the frontonasal eminence, but pathogenetic heterogeneity existing in this condition suggests that other aetiologies should be considered (GuionAlmeida et al., 1996). The involvement of other… CONTINUE READING