Severe mannitol-induced hyponatremia complicating transurethral prostatic resection.

@article{Kirschenbaum1979SevereMH,
  title={Severe mannitol-induced hyponatremia complicating transurethral prostatic resection.},
  author={Michael A Kirschenbaum},
  journal={The Journal of urology},
  year={1979},
  volume={121 5},
  pages={687-8}
}
A case is presented in which the absorption of mannitol irrigation solution across prostatic veins resulted in severe hyponatremia in a patient undergoing transurethral prostatic resection. Since hyposmolality of the extracellular fluid was not seen because of the presence of mannitol the patient was asymptomatic despite a rapid decrease in the serum sodium concentration to 99 mEq./l. The importance of distinguishing dilutional hyponatremia from hyponatremia with normal or elevated osmolality… CONTINUE READING