Severe intestinal ischemia can trigger cardiovascular collapse and sudden death via a parasympathetic mechanism.

@article{Penn2011SevereII,
  title={Severe intestinal ischemia can trigger cardiovascular collapse and sudden death via a parasympathetic mechanism.},
  author={Alexander H. Penn and Geert W Schmid-Sch{\"o}nbein},
  journal={Shock},
  year={2011},
  volume={36 3},
  pages={
          251-62
        }
}
Hemorrhagic shock and splanchnic arterial occlusion (SAO) followed by reperfusion are associated with high mortality. However, rapid cardiovascular failure and death may also occur before reperfusion in hemorrhagic shock and SAO. We show in a rat SAO model that, upon gut ischemia, mean arterial blood pressure transiently elevates and then drops fatally in one of two time courses: (i) gradually over ∼1 to 3 h or (ii) rapidly (often by >80 mmHg) over a period of 1 to 6 min. We hypothesize that… CONTINUE READING
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