Severe impairment of antioxidant system in human hepatoma.

@article{Corrocher1986SevereIO,
  title={Severe impairment of antioxidant system in human hepatoma.},
  author={Roberto Corrocher and Massimo Casaril and Giuseppe Bellisola and Giovanni Battista Gabrielli and Nicola Nicoli and Gian Cesare Guidi and G de Sandre},
  journal={Cancer},
  year={1986},
  volume={58 8},
  pages={
          1658-62
        }
}
Catalase (CAT), glutathione-peroxidase (GSH-Px) activity and reduced glutathione content (GSH) were measured in patients who had hepatocellular carcinoma, and values compared with those of normal liver and liver adjacent to neoplastic tissue. The results showed a remarkable reduction of CAT in tumor and corresponding tumor-free tissue (P less than 0.001 and P less than 0.02, respectively). All neoplastic samples had a significant lower activity of CAT than the corresponding adjacent tumor-free… CONTINUE READING
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