Severe hyponatremia associated with thiazide diuretic use.

  title={Severe hyponatremia associated with thiazide diuretic use.},
  author={Gurkiran K Sardar and Wesley P Eilbert},
  journal={The Journal of emergency medicine},
  volume={48 3},
BACKGROUND Thiazide diuretics are commonly used as first-line antihypertensive agents. Hyponatremia is a reported, though uncommon, complication of thiazide use. Although the exact mechanism of thiazide-induced hyponatremia (TIH) is unclear, it can be a significant cause of morbidity and mortality. CASE REPORT We report a 69-year-old man with generalized weakness beginning 2 weeks after starting hydrochlorothiazide (HCTZ). Evaluation revealed a serum sodium level of 120 mmol/L. The patient… CONTINUE READING