Severe hypertension after liver transplantation in alpha 1 antitrypsin deficiency.

@article{NobleJamieson1990SevereHA,
  title={Severe hypertension after liver transplantation in alpha 1 antitrypsin deficiency.},
  author={Gabriele Noble-Jamieson and Nicholas D Barnes and Sathia Thiru and A. P. Mowat},
  journal={Archives of disease in childhood},
  year={1990},
  volume={65 11},
  pages={1217-21}
}
Five children with alpha 1 antitrypsin deficiency and terminal liver disease received liver grafts; all five became hypertensive and four developed hypertensive encephalopathy. There was evidence of renal disease preoperatively and renal biopsy specimens showed variable glomerulonephritic histology with IgA nephropathy in one, mesangial-proliferative changes in two, and mesangio-capillary glomerulonephritis type I in two. Four hypertensive episodes were preceded by a fall in creatinine… CONTINUE READING
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