Severe human metapneumovirus infection in hospitalized children.


Human metapneumovirus is a recently discovered pathogen that causes upper and lower respiratory tract disease in children. This study describes the course of illness in hospitalized children with this infection. During a 6-month period, 11 children were diagnosed with human metapneumovirus infection by reverse transcription-polymerase chain reaction. Oxygen supplementation was required for 82% of patients. Severe disease developed in 45%, and mechanical ventilation was required. An apparent life-threatening event was the indication for hospitalization of 27% of patients infected with human metapneumovirus. Children with underlying asthma or neuromuscular disease had a prolonged hospitalization.


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@article{Estrada2007SevereHM, title={Severe human metapneumovirus infection in hospitalized children.}, author={Benjamin Estrada and Macharia Carter and Sailen Barik and Rosa A Vidal and Donald E Herbert and Keith M. Ramsey}, journal={Clinical pediatrics}, year={2007}, volume={46 3}, pages={258-62} }