Severe facial clefts in acrofacial dysostosis: a consequence of prenatal exposure to mycophenolate mofetil?

@article{Schoner2008SevereFC,
  title={Severe facial clefts in acrofacial dysostosis: a consequence of prenatal exposure to mycophenolate mofetil?},
  author={Katharina Schoner and Johannes Steinhard and Jens Figiel and Helga Rehder},
  journal={Obstetrics and gynecology},
  year={2008},
  volume={111 2 Pt 2},
  pages={483-6}
}
BACKGROUND Immunosuppressants are teratogenic in mice, rats, and rabbits and cause prenatal growth restriction in humans. As yet, there has been no proven teratogenicity in humans. CASE We present a chromosomally normal fetus with severe acrofacial dysostosis and orofacial clefts. These were bilateral transverse and oblique clefts and defects of the midface. In addition, there were preaxial limb anomalies with digitalization of thumbs and internal cardiovascular, gastrointestinal, and… CONTINUE READING

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Oxford Medical Databases: London Dysmorphology Database, Version 3.0–Dysmorphology Photo Library on CD-ROM Version 3.0

  • RM Winter, M. Baraitser
  • 2001

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